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Products Details
Product Description
– A201A is a aminoacylnucleoside antibiotic with antibacterial activities. A201A is highly effective against Gram-positive and most Gram-negative anaerobic bacteria. A201A inhibits tRNA accommodation during translation[1][2].
Web ID
– HY-125496
Shipping
– Room temperature
Molecular Formula
– C37H50N6O14
References
– [1]Wang J, et al. Bioinspired Total Synthesis of Complex Nucleoside Antibiotics A201A, A201D and A201E. Angew Chem Int Ed Engl. 2023 Jan 16;62(3):e202213810.|[2]Nie S, et al. Total synthesis of nucleoside antibiotic A201A. J Am Chem Soc. 2014 Mar 19;136(11):4157-60.
CAS Number
– 37305-78-5
Molecular Weight
– 802.82
SMILES
– CN(C)C1=C(N=CN2[C@@H]3O[C@H](CO)[C@@H](NC(/C(C)=C/C4=CC=C(C=C4)O[C@@H]([C@@H](O)[C@@H]/5O)OC5=C(OC)CO[C@@H]6[C@H]([C@H]([C@@H]([C@H](O6)C)OC)OC)O)=O)[C@H]3O)C2=NC=N1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
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