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A1AT modulator 2

$320$8,500

Products Details

Product Description

– A1AT modulator 2 (compound 33) is a modulator of A1AT (α-1 antitrypsin) with an IC50 value of >1.0 μM and an EC50 value of <0.4 μM. A1AT modulator 2 can be used for the research of infection and inflammation[1].

Web ID

– HY-134863

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C27H22FN3O3

References

– [1]Bandarage, Upul Keerthi, et al. Pyrrolo[2,3-f]indazole derivatives as modulators of α-1 antitrypsin and their preparation. US20200361939. 2020.

CAS Number

– 2555004-05-0

Molecular Weight

– 455.48

Compound Purity

– 98.32

SMILES

– O=C(O)C1=CC=C(C2=C(C3CCOCC3)N(C4=CC=C(F)C=C4)C5=CC6=C(NN=C6)C=C52)C=C1

Clinical Information

– No Development Reported

Research Area

– Infection; Inflammation/Immunology

Solubility

– DMSO : 50 mg/mL (ultrasonic)

Target

– Others

Pathway

– Others

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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