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A-967079
SKU
HY-108463-10 mg
Category Reference compound
Tags Inflammation/Immunology, Membrane Transporter/Ion Channel;Neuronal Signaling, TRP Channel
$70 – $640
Products Details
Product Description
– A-967079 is a selective TRPA1 receptor antagonist with IC50s of 67 nM and 289 nM at human and rat TRPA1 receptors, respectively, and has good penetration into the CNS.
Web ID
– HY-108463
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C12H14FNO
References
– [1]McGaraughty S, et al. TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats. Mol Pain. 2010 Mar 5;6:14.
CAS Number
– 1170613-55-4
Molecular Weight
– 207.24
Compound Purity
– 99.30
SMILES
– CCC(/C(C)=C/C1=CC=C(F)C=C1)=NO.[E].[E]
Clinical Information
– Phase 1
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– TRP Channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.