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A-933548

Products Details

Product Description

– A-933548 is a potent and selective inhibitor of calpain, with a Ki of 18 nM. A-933548 can be used for the research of Alzheimer’s disease[1].

Web ID

– HY-113639

Shipping

– Room temperature

Molecular Formula

– C25H21N5O3

References

– [1]Kling A, et, al. Discovery of Novel and Highly Selective Inhibitors of Calpain for the Treatment of Alzheimer’s Disease: 2-(3-Phenyl-1H-pyrazol-1-yl)-nicotinamides. J Med Chem. 2017 Aug 24;60(16):7123-7138.

CAS Number

– 1037826-43-9

Molecular Weight

– 439.47

SMILES

– O=C(C1=C(N=CC=C1)N2N=C(C=C2)C3=CC=CC=C3)NC(CC4=CC=CC=C4)C(C(N)=O)=O

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Proteasome

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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