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A-887826
$120 – $1,350
Products Details
Product Description
– A-887826 is a potent, selective, oral bioavailable and voltage-dependent Na(v)1.8 sodium channel blocker with an IC50 of 11 nM . A-887826 attenuates neuropathic tactile allodynia in vivo[1].
Web ID
– HY-100080
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C26H29ClN4O3
References
– [1]Zhang XF, et al. A-887826 is a structurally novel, potent and voltage-dependent Na(v)1.8 sodium channel blocker that attenuates neuropathic tactile allodynia in rats. Neuropharmacology. 2010 Sep;59(3):201-7.
CAS Number
– 1266212-81-0
Molecular Weight
– 480.99
Compound Purity
– 99.76
SMILES
– O=C(C1=CC(C2=CC=C(OCCCC)C(Cl)=C2)=CN=C1)NCC3=CC=CN=C3N4CCOCC4
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– Sodium Channel
Isoform
– Nav1.8
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
