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A-425619
SKU
HY-110292-Get quote
Category Reference compound
Tags Inflammation/Immunology, Membrane Transporter/Ion Channel;Neuronal Signaling, TRP Channel
Products Details
Product Description
– A-425619, a potent and selective TRPV1 receptor antagonist, is effective in alleviating acute and chronic inflammatory pain and postoperative pain[1].
Web ID
– HY-110292
Shipping
– Room temperature
Molecular Formula
– C18H14F3N3O
References
– [1]Sampurna Chakrabarti, et al. Acute inflammation sensitizes knee-innervating sensory neurons and decreases mouse digging behavior in a TRPV1-dependent manner. Neuropharmacology. 2018 Dec;143:49-62.Â
CAS Number
– 581809-67-8
Molecular Weight
– 345.32
SMILES
– FC(F)(F)C(C=C1)=CC=C1CNC(NC2=CC=CC3=C2C=CN=C3)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– TRP Channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.