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Products Details
Product Description
– Aβ-IN-4 (compound 12) is a potent amyloid β (Aβ) inhibitor. Aβ-IN-4 inhibits Aβ42 aggregation. However, Aβ-IN-4 can not alleviate the neurotoxicity of Aβ42 in SH-SY5Y cells. Aβ-IN-4 can not change the aggregation state of Aβ42 into a nontoxic one[1].
Web ID
– HY-146140
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C33H43N5O7
References
– [1]Tanaka F, et al. Design and synthesis of β-strand-fixed peptides inhibiting aggregation of amyloid β-protein. Bioorg Med Chem. 2020 Sep 15;28(18):115676.
CAS Number
– 2477606-97-4
Molecular Weight
– 621.72
SMILES
– O=C(N[C@@H](CC1=CC=C(OC/C=C/C[C@@H](C(N2)=O)NC([C@@H](N)CC(C)C)=O)C=C1)C(N[C@@H](C)C(O)=O)=O)[C@@H]2CC3=CC=CC=C3
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Amyloid-β
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
