9-Hydroxyoctadecanoic acid

SKU HY-N11692-1 mg Category Tags , ,

$50$360

Products Details

Product Description

– 9-Hydroxyoctadecanoic acid (9-HSA) is an HDAC1 inhibitor that inhibits ∼66.4% HDAC1 enzymatic activity at 5 μM. 9-Hydroxyoctadecanoic acid shows anticancer activity[1].

Web ID

– HY-N11692

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Molecular Formula

– C18H36O3

References

– [1]Calonghi N, et al. Histone deacetylase 1: a target of 9-hydroxystearic acid in the inhibition of cell growth in human colon cancer. J Lipid Res. 2005 Aug;46(8):1596-603.|[2]Calonghi N, et al. 9-Hydroxystearic acid upregulates p21(WAF1) in HT29 cancer cells. Biochem Biophys Res Commun. 2004 Jan 30;314(1):138-42.

CAS Number

– 3384-24-5

Molecular Weight

– 300.48

Compound Purity

– 98.0

SMILES

– O=C(CCCCCCCC(CCCCCCCCC)O)O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : ≥ 100 mg/mL

Target

– HDAC

Isoform

– HDAC1

Pathway

– Cell Cycle/DNA Damage;Epigenetics

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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