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Products Details
Product Description
– 8BTC (compound 4w) is a potent covalent Notum inhibitor with IC50 of 2.5 nM[1].
Web ID
– HY-149818
Shipping
– Room temperature
Molecular Formula
– C10H9Cl2NO
References
– [1]Benjamin N Atkinson, et al. Designed switch from covalent to non-covalent inhibitors of carboxylesterase Notum activity. Eur J Med Chem. 2023 May 5;251:115132.
Molecular Weight
– 230.09
SMILES
– CC(N1CCC2=C1C=CC(Cl)=C2Cl)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Wnt
Pathway
– Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
