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Products Details
Product Description
– 8304-vs is a macrocyclic anti-Plasmodial agent that covalently and irreversibly targets the Plasmodium proteasome. 8304-vs effectively inhibits the growth of Plasmodium falciparum[1].
Web ID
– HY-156105
Shipping
– Room temperature
Molecular Formula
– C35H53N5O8S
References
– [1]Bennett JM, et al. Covalent Macrocyclic Proteasome Inhibitors Mitigate Resistance in Plasmodium falciparum. ACS Infect Dis. 2023 Sep 15..
Molecular Weight
– 703.89
SMILES
– O=C1N(CCC1)[C@@H](CC2=CC(OCCCC[C@H](N3)C(N[C@H](/C=C/S(C)(=O)=O)CC(C)C)=O)=CC=C2)C(N[C@H](C3=O)CCN4CCOCC4)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Parasite;Proteasome
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
