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7-Oxostaurosporine
$761
Only 1000 item(s) left in stock.
Products Details
Product Description
– 7-Oxostaurosporine is a potent protein kinase C (PKC) inhibitor that effectively inhibits tumor growth by inducing apoptosis and inhibiting the nuclear factor (NF)-κB/p-p65 pathway[1][2].
Web ID
– HY-120515
Shipping
– Room temperature
Molecular Formula
– C28H24N4O4
References
– [1]Masashi Maekawa, et al. Staurosporines decrease ORMDL proteins and enhance sphingomyelin synthesis resulting in depletion of plasmalemmal phosphatidylserine. Sci Rep. 2016 Nov 2;6:35762. |[2]Feng Song, et al. The anticancer activity of carbazole alkaloids. Arch Pharm (Weinheim). 2022 Jan;355(1):e2100277.
CAS Number
– 125035-83-8
Molecular Weight
– 480.51
SMILES
– [H][C@@]12N3C4=C(C5=C(C6=C4C7=C3C=CC=C7)C(NC6=O)=O)N(C8=C5C=CC=C8)[C@](C)([C@@H]([C@@H](C2)NC)OC)O1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– PKC
Pathway
– Epigenetics;TGF-beta/Smad
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
