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Products Details
Product Description
– 7-Ethoxyresorufin-d5 is deuterium labeled 7-Ethoxyresorufin. 7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase[1][2].
Web ID
– HY-D0145S
Shipping
– Room temperature
Molecular Formula
– C14H6D5NO3
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]C G Li, et al. Inhibition of NO-medicate responses by 7-ethoxyresorufin, a substrate and competitive inhibitor of cytochrome P450. Br J Pharmacol. 1996 May;118(1):57-62.|[3]Thomas K H Chang, et al. Enzymatic analysis of cDNA-expressed human CYP1A1, CYP1A2, and CYP1B1 with 7-ethoxyresorufin as substrate. Methods Mol Biol. 2006;320:85-90.
CAS Number
– 2749329-28-8
Molecular Weight
– 246.27
SMILES
– O=C1C=C2OC3=CC(OC([2H])([2H])C([2H])([2H])[2H])=CC=C3N=C2C=C1
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Cytochrome P450;Isotope-Labeled Compounds;NO Synthase
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease;Others
Product type
– Isotope-Labeled Compounds
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