7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine

Products Details

Product Description

– 7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Web ID

– HY-152436

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C14H19N5O6

References

– [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

CAS Number

– 2389988-23-0

Molecular Weight

– 353.33

SMILES

– OC[C@@H]1[C@H](O)[C@@H](O)[C@H](N(C(N2CC3CC3)=O)C4=C2C(NC(N)=N4)=O)O1

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– 10 mM in DMSO

Target

– Nucleoside Antimetabolite/Analog

Pathway

– Cell Cycle/DNA Damage

Product type

– Oligonucleotides

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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