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7-Aminomethyl-10-methyl-11-fluoro camptothecin (TFA)
SKU
HY-132160A-1 mg
Category Reference compound
Tags ADC Cytotoxin, Antibody-drug Conjugate/ADC Related, Cancer
$620 – $2,960
Products Details
Product Description
– 7-Aminomethyl-10-methyl-11-fluoro camptothecin TFA is a cytotoxin of MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (HY-132158). 7-Aminomethyl-10-methyl-11-fluoro camptothecin TFA can be used for the synthesis of camptothecin antibody-drug conjugate (ADC)[1].
Web ID
– HY-132160A
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture and light)
Shipping
– Blue Ice
Molecular Formula
– C24H21F4N3O6
References
– [1]Li W, et, al. Synthesis and Evaluation of Camptothecin Antibody-Drug Conjugates. ACS Med Chem Lett. 2019 Sep 6;10(10):1386-1392.
Molecular Weight
– 523.43
Compound Purity
– 95.73
SMILES
– NCC1=C2C(C(N3C2)=CC([C@]4(CC)O)=C(C3=O)COC4=O)=NC5=CC(F)=C(C=C51)C.OC(C(F)(F)F)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Cytotoxin
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.