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7-Acetoxy-4-methylcoumarin
SKU
HY-137877-Get quote
Category Reference compound
Tags Gutathione S-transferase, Metabolic Enzyme/Protease, Others
Products Details
Product Description
– 7-Acetoxy-4-methylcoumarin is an inhibitor of GST.7-Acetoxy-4-methylcoumarin inhibits AFB1-DNA binding in vitro with 36.7% inhibition[1][2].
Web ID
– HY-137877
Shipping
– Room temperature
Molecular Formula
– C12H10O4
References
– [1]Raj HG, et al. Mechanism of biochemical action of substituted benzopyran-2-ones. Part 8: Acetoxycoumarin: protein transacetylase specificity for aromatic nuclear acetoxy groups in proximity to the oxygen heteroatom. Bioorg Med Chem. 2001 May;9(5):1085-9.|[2]Feuer, G, et al. Induction of drug-metabolizing enzymes of rat liver by derivatives of coumarin. Canadian Journal of Physiology and Pharmacology, 48(4), 232–240.
CAS Number
– 2747-05-9
Molecular Weight
– 218.21
SMILES
– O=C1C=C(C)C2=CC=C(OC(C)=O)C=C2O1
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Gutathione S-transferase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.