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Products Details
Product Description
– 7-Acetoxy-4-methylcoumarin is an inhibitor of GST.7-Acetoxy-4-methylcoumarin inhibits AFB1-DNA binding in vitro with 36.7% inhibition[1][2].
Web ID
– HY-137877
Shipping
– Room temperature
Molecular Formula
– C12H10O4
References
– [1]Raj HG, et al. Mechanism of biochemical action of substituted benzopyran-2-ones. Part 8: Acetoxycoumarin: protein transacetylase specificity for aromatic nuclear acetoxy groups in proximity to the oxygen heteroatom. Bioorg Med Chem. 2001 May;9(5):1085-9.|[2]Feuer, G, et al. Induction of drug-metabolizing enzymes of rat liver by derivatives of coumarin. Canadian Journal of Physiology and Pharmacology, 48(4), 232–240.
CAS Number
– 2747-05-9
Molecular Weight
– 218.21
SMILES
– O=C1C=C(C)C2=CC=C(OC(C)=O)C=C2O1
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Gutathione S-transferase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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