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Products Details
Product Description
– 6BrCaQ-C10-TPP is a potent mitochondrial heat shock protein TRAP1 inhibitor, with antiproliferative activity in various human cancer cells (IC50=0.008-0.30 μM). 6BrCaQ-C10-TPP can also induces mitochondrial membrane disturbance[1].
Web ID
– HY-144831
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C45H47Br2N2O3P
References
– [1]Mathieu C, et, al. Synthesis and antiproliferative activity of 6BrCaQ-TPP conjugates for targeting the mitochondrial heat shock protein TRAP1. Eur J Med Chem. 2022 Feb 5;229:114052.
Molecular Weight
– 854.65
SMILES
– CN1C(C(NC(C2=CC=C(C=C2)OCCCCCCCCCC[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)=O)=CC6=CC(Br)=CC=C61)=O.[Br-]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HSP
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
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