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5,6,7-Trimethoxyflavone

$96$768

Products Details

Product Description

– 5,6,7-Trimethoxyflavone is a novel p38-α MAPK inhibitor with an anti-inflammatory effect. 5,6,7-Trimethoxyflavone is isolated from several plants including Zeyhera tuberculosa, Callicarpa japonica, and Kickxia lanigera[1].

Web ID

– HY-110398

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C18H16O5

References

– [1]Hassan AHE, et al. Repurposing mosloflavone/5,6,7-trimethoxyflavone-resveratrol hybrids: Discovery of novel p38-α MAPK inhibitors as potent interceptors of macrophage-dependent production of proinflammatory mediators. Eur J Med Chem. 2019 Jul 9;180:253-267.

CAS Number

– 973-67-1

Molecular Weight

– 312.32

Compound Purity

– 98.76

SMILES

– O=C1C=C(C2=CC=CC=C2)OC3=CC(OC)=C(OC)C(OC)=C13

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology; Cancer

Solubility

– DMSO : 33.33 mg/mL (ultrasonic)

Target

– p38 MAPK

Pathway

– MAPK/ERK Pathway

Product type

– Natural Products

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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