Download Files:
Products Details
Product Description
– 5-LOX-IN-5 (Compound 29) is a 5-LOX inhibitor (IC50: 56 nM). 5-LOX-IN-5 can be used for research of neurodegenerative diseases[1].
Web ID
– HY-149476
Shipping
– Room temperature
Molecular Formula
– C19H18BrN3O2S
References
– [1]Marković A, et al. Thiazole derivatives as dual inhibitors of deoxyribonuclease I and 5-lipoxygenase: A promising scaffold for the development of neuroprotective drugs. Chem Biol Interact. 2023 Aug 25;381:110542.
Molecular Weight
– 432.33
SMILES
– OC1=CC=C(NC2=NC(C3=CC=C(N4CCOCC4)C(Br)=C3)=CS2)C=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Lipoxygenase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
