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5-LOX-IN-3

Products Details

Product Description

– 5-LOX-IN-3 (Compound 14) is a 5-Lipoxygenase inhibitor (IC50: <1 μM). 5-LOX-IN-3 can be used for research of inflammatory diseases, cancer, stroke and Alzheimer's disease[1].

Web ID

– HY-153279

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C19H16ClN5O

References

– [1]Jaeseung Kim, et al. 2-amino-benzimidazole derivatives and their use as 5-lipoxygenase and/or prostaglandin e synthase inhibitors. Patent WO2016016421A1.

CAS Number

– 1875061-47-4

Molecular Weight

– 365.82

SMILES

– NC1=CC=C2N=C(NCC3=NC=C(OC4=CC=C(Cl)C=C4)C=C3)NC2=C1

Clinical Information

– No Development Reported

Research Area

– Cancer; Inflammation/Immunology; Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Lipoxygenase

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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