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Products Details
Product Description
– 5-Iodo-A-85380 dihydrochloride is a selective ligand of nAChR. 5-Iodo-A-85380 dihydrochloride binds to α4β2 nAChRs in rat and human brain with Kds of 12 and 14 pM,respectively[1].
Web ID
– HY-107686
Shipping
– Room temperature
Molecular Formula
– C9H13Cl2IN2O
References
– [1]Mukhin AG, et al. 5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors. Mol Pharmacol. 2000 Mar;57(3):642-9.
CAS Number
– 1217837-17-6
Molecular Weight
– 363.02
SMILES
– IC1=CC(OC[C@@H]2CCN2)=CN=C1.[H]Cl.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– nAChR
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
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