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5-Iminodaunorubicin (hydrochloride)
$350 – $1,700
Products Details
Product Description
– 5-Iminodaunorubicin hydrochloride is a quinone-modified anthracycline that retains antitumor activity[1]. 5-Iminodaunorubicin hydrochloride produces protein-concealed DNA strand breaks in cancer cells[2].
Web ID
– HY-138645A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C27H31ClN2O9
References
– [1]R A Jensen, et al. Electrocardiographic and transmembrane potential effects of 5-iminodaunorubicin in the rat. Cancer Res. 1984 Sep;44(9):4030-9.|[2]L A Zwelling, et al. Cytotoxicity and DNA strand breaks by 5-iminodaunorubicin in mouse leukemia L1210 cells: comparison with adriamycin and 4′-(9-acridinylamino)methanesulfon-m-anisidide. Cancer Res. 1982 Jul;42(7):2687-91.
CAS Number
– 67324-99-6
Molecular Weight
– 563.00
Compound Purity
– 95.65
SMILES
– COC(C=CC=C1C(C2=C(O)C(C[C@@](C(C)=O)(C[C@@H]3O[C@@H]4O[C@H]([C@H]([C@H](C4)N)O)C)O)=C3C(O)=C52)=O)=C1C5=N.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 230 mg/mL (ultrasonic)|H2O : 8.33 mg/mL (ultrasonic)
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
