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5-Hydroxymethyl-2′-deoxyuridine
$80 – $250
Products Details
Product Description
– 5-Hydroxymethyl-2′-deoxyuridine is a nucleoside analog. 5-Hydroxymethyl-2′-deoxyuridine inhibits the replication of multiple human leukemia cell lines with IC50 values of 1.7-5.8 μM. 5-Hydroxymethyl-2′-deoxyuridine prolongs the survival of mice carrying L1210 leukemia. 5-Hydroxymethyl-2′-deoxyuridine can be used for the research of cell replication and leukemia[1][2][3].
Web ID
– HY-129983
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C10H14N2O6
References
– [1]Shiau GT, et al. Synthesis and biological activities of 5-(hydroxymethyl, azidomethyl, or aminomethyl)-2′-deoxyuridine and related 5′-substituted analogues. J Med Chem. 1980 Feb;23(2):127-33.|[2]Kahilainen LI, et al. 5-Hydroxymethyl-2′-deoxyuridine. Cytotoxicity and DNA incorporation studied by using a novel [2-14C]-derivative with normal and leukemic human hematopoietic cells. Acta Chem Scand B. 1985;39(6):477-84.|[3]JA Vilpo, et al. 5-Hydroxymethyl-2′-Deoxyuridine: Studies of Antileukemic Properties in Vitro and in Vivo. Nucleosides and Nucleotides . 1987.
CAS Number
– 5116-24-5
Molecular Weight
– 258.23
Compound Purity
– 99.98
SMILES
– O[C@H]1C[C@H](N2C(NC(C(CO)=C2)=O)=O)O[C@@H]1CO
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– DMSO : ≥ 125 mg/mL
Target
– HSV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
