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Products Details
Product Description
– 5-HT6/5-HT2AR antagonist-1 is a potent dual 5-HT6/5-HT2AR antagonist with Ki values of 11 nM and 39 nM, respectively[1].
Web ID
– HY-145862
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C21H26N6S
References
– [1]Katarzyna Kucwaj-Brysz, et al. An exit beyond the pharmacophore model for 5-HT 6 R agents – a new strategy to gain dual 5-HT 6/5-HT 2A action for triazine derivatives with procognitive potential. Bioorg Chem. 2022 Apr;121:105695.
CAS Number
– 2763654-60-8
Molecular Weight
– 394.54
SMILES
– NC1=NC(N2CCN(C)CC2)=NC(C(C)(SC3=CC=C4C=CC=CC4=C3)C)=N1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– 5-HT Receptor
Isoform
– 5-HT2 Receptor;5-HT6 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
