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Products Details
Product Description
– 5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione (Compound 4) has antimicrobial, anti-diabetic and antioxidant activities. 5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione inhibits B. subtilis, S. aureus, K. pneumonia, E. coli, and S. typhi with MICs of 4.5-9.9 μΜ/mL, and inhibits A. niger and C. albicans with MICs of 4.99 μΜ/mL[1].
Web ID
– HY-131044
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C10H6N2O4S
References
– [1]Elkamhawy A, et al. Thiazolidine-2,4-dione-based irreversible allosteric IKK-β kinase inhibitors: Optimization into in vivo active anti-inflammatory agents. Eur J Med Chem. 2020 Feb 15;188:111955.
CAS Number
– 36140-65-5
Molecular Weight
– 250.23
SMILES
– O=C(NC/1=O)SC1=CC2=CC=CC=C2[N+]([O-])=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial;Fungal
Pathway
– Anti-infection
Product type
– Reference compound
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