5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione

SKU HY-131044-Get quote Category Tags , ,

Products Details

Product Description

– 5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione (Compound 4) has antimicrobial, anti-diabetic and antioxidant activities. 5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione inhibits B. subtilis, S. aureus, K. pneumonia, E. coli, and S. typhi with MICs of 4.5-9.9 μΜ/mL, and inhibits A. niger and C. albicans with MICs of 4.99 μΜ/mL[1].

Web ID

– HY-131044

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C10H6N2O4S

References

– [1]Elkamhawy A, et al. Thiazolidine-2,4-dione-based irreversible allosteric IKK-β kinase inhibitors: Optimization into in vivo active anti-inflammatory agents. Eur J Med Chem. 2020 Feb 15;188:111955.

CAS Number

– 36140-65-5

Molecular Weight

– 250.23

SMILES

– O=C(NC/1=O)SC1=CC2=CC=CC=C2[N+]([O-])=O

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– Bacterial;Fungal

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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