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4E2RCat
SKU
HY-100733-1 mg
Category Reference compound
Tags Anti-infection;Autophagy;Cell Cycle/DNA Damage, Autophagy;Eukaryotic Initiation Factor (eIF);Virus Protease, Neurological Disease
$132 – $2,520
Products Details
Product Description
– 4E2RCat is an inhibitor of eIF4E-eIF4G interaction with an IC50 of 13.5 μM.
Web ID
– HY-100733
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C22H14ClNO4S2
References
– [1]Cencic R, et al. Blocking eIF4E-eIF4G interaction as a strategy to impair coronavirus replication. J Virol. 2011 Jul;85(13):6381-9.
CAS Number
– 432499-63-3
Molecular Weight
– 455.93
Compound Purity
– 98.0
SMILES
– O=C(O)C1=CC(C2=CC=C(/C=C(SC(N3CC4=CC=CC=C4)=S)/C3=O)O2)=CC=C1Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 23.33 mg/mL (ultrasonic)
Target
– Autophagy;Eukaryotic Initiation Factor (eIF);Virus Protease
Isoform
– eIF4
Pathway
– Anti-infection;Autophagy;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.