4E2RCat

$132$2,520

Products Details

Product Description

– 4E2RCat is an inhibitor of eIF4E-eIF4G interaction with an IC50 of 13.5 μM.

Web ID

– HY-100733

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C22H14ClNO4S2

References

– [1]Cencic R, et al. Blocking eIF4E-eIF4G interaction as a strategy to impair coronavirus replication. J Virol. 2011 Jul;85(13):6381-9.

CAS Number

– 432499-63-3

Molecular Weight

– 455.93

Compound Purity

– 98.0

SMILES

– O=C(O)C1=CC(C2=CC=C(/C=C(SC(N3CC4=CC=CC=C4)=S)/C3=O)O2)=CC=C1Cl

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– DMSO : 23.33 mg/mL (ultrasonic)

Target

– Autophagy;Eukaryotic Initiation Factor (eIF);Virus Protease

Isoform

– eIF4

Pathway

– Anti-infection;Autophagy;Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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