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Products Details
Product Description
– 4,5′-Dimethylangelicin-NHS is a modified 4,5′-Dimethylangelicin containing an NHS. 4,5′-Dimethylangelicin is an angular furocoumarin with photochemical and photosensitizing properties. 4,5′-Dimethylangelicin can inhibit the DNA and RNA syntheses in Ehrlich ascites tumor cells alter irradiation at 365 nm. 4,5′-Dimethylangelicin has potential as a photochemotherapy agent[1][2].
Web ID
– HY-150015
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H19NO7S
References
– [1]Bordin F, et al. 4,5′-dimethylangelicin: a new DNA-photobinding monofunctional agent. Photochem Photobiol. 1979 Jun;29(6):1063-70.|[2]Guiotto A, et al. A new water soluble derivative of 4,5′-dimethylangelicin as a potential agent for photochemotherapy. Farmaco Sci. 1981 Jul;36(7):536-50.
Molecular Weight
– 429.44
SMILES
– CC1=CC(OC2=C1C=CC3=C2C(CSCCC(ON4C(CCC4=O)=O)=O)=C(C)O3)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
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