Download Files:
Products Details
Product Description
– 4,5′-Dimethylangelicin-NHS is a modified 4,5′-Dimethylangelicin containing an NHS. 4,5′-Dimethylangelicin is an angular furocoumarin with photochemical and photosensitizing properties. 4,5′-Dimethylangelicin can inhibit the DNA and RNA syntheses in Ehrlich ascites tumor cells alter irradiation at 365 nm. 4,5′-Dimethylangelicin has potential as a photochemotherapy agent[1][2].
Web ID
– HY-150015
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H19NO7S
References
– [1]Bordin F, et al. 4,5′-dimethylangelicin: a new DNA-photobinding monofunctional agent. Photochem Photobiol. 1979 Jun;29(6):1063-70.|[2]Guiotto A, et al. A new water soluble derivative of 4,5′-dimethylangelicin as a potential agent for photochemotherapy. Farmaco Sci. 1981 Jul;36(7):536-50.
Molecular Weight
– 429.44
SMILES
– CC1=CC(OC2=C1C=CC3=C2C(CSCCC(ON4C(CCC4=O)=O)=O)=C(C)O3)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
