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Products Details
Product Description
– 4-Methylhistamine is a potent agonist of histamine 4 receptor (H4R). 4-Methylhistamine has the potential for the research of immune-related diseases such as cancer and autoimmune disorders[1][2].
Web ID
– HY-W580721
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C6H11N3
References
– [1]Ahmad SF, et al. Stimulation of the histamine 4 receptor with 4-methylhistamine modulates the effects of chronic stress on the Th1/Th2 cytokine balance. Immunobiology. 2015;220(3):341-349.|[2]Kim CH, et al. Inhibitory Effect of Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice by Histamine H4 Receptor Agonist 4-Methylhistamine. Scand J Immunol. 2016 Jun;83(6):409-17.
CAS Number
– 36507-31-0
Molecular Weight
– 125.17
SMILES
– NCCC1=C(C)N=CN1
Clinical Information
– No Development Reported
Research Area
– Cancer, Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Histamine Receptor
Pathway
– GPCR/G Protein, Immunology/Inflammation, Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
