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Products Details
Product Description
– 4-Hydroxyoxyphenbutazone kills both replicating and nonreplicating (NR) Mycobacterium tuberculosis (Mtb), including Mtb resistant to standard agents. 4-Hydroxyoxyphenbutazone is a potent inhibitor of cytokine production. 4-Hydroxyoxyphenbutazone is an immunosuppressive agent and has the potential for rheumatoid arthritis research[1][2].
Web ID
– HY-108050
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C19H20N2O4
References
– [1]Ben Gold, et al. Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials. |[2]Anja Ten Brinke, et al. 4-Hydroxy-oxyphenbutazone is a potent inhibitor of cytokine production. Eur Cytokine Netw. 2005 Jun;16(2):144-51.
CAS Number
– 55648-39-0
Molecular Weight
– 340.37
SMILES
– O=C1N(N(C(C1(CCCC)O)=O)C2=CC=C(C=C2)O)C3=CC=CC=C3
Clinical Information
– No Development Reported
Research Area
– Infection; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
