Products Details

Product Description

– 4-Hydroxyoxyphenbutazone kills both replicating and nonreplicating (NR) Mycobacterium tuberculosis (Mtb), including Mtb resistant to standard agents. 4-Hydroxyoxyphenbutazone is a potent inhibitor of cytokine production. 4-Hydroxyoxyphenbutazone is an immunosuppressive agent and has the potential for rheumatoid arthritis research[1][2].

Web ID

– HY-108050

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C19H20N2O4

References

– [1]Ben Gold, et al. Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials. |[2]Anja Ten Brinke, et al. 4-Hydroxy-oxyphenbutazone is a potent inhibitor of cytokine production. Eur Cytokine Netw. 2005 Jun;16(2):144-51.

CAS Number

– 55648-39-0

Molecular Weight

– 340.37

SMILES

– O=C1N(N(C(C1(CCCC)O)=O)C2=CC=C(C=C2)O)C3=CC=CC=C3

Clinical Information

– No Development Reported

Research Area

– Infection; Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Bacterial

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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