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4-Hydroxy Atorvastatin lactone

$931

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Products Details

Product Description

– 4-Hydroxy Atorvastatin lactone is a metabolite of Atorvastatin (HY-B0589). Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids[1].

Web ID

– HY-126852

Shipping

– Room temperature

Molecular Formula

– C33H33FN2O5

References

– [1]Jemal M, et al. Quantitation of the acid and lactone forms of atorvastatin and its biotransformation products in human serum by high-performance liquid chromatography with electrospray tandem mass spectrometry. Rapid Commun Mass Spectrom. 1999;13(11):1003-15.

CAS Number

– 163217-70-7

Molecular Weight

– 556.62

SMILES

– O=C(C1=C(C(C)C)N(CC[C@@H]2C[C@@H](O)CC(O2)=O)C(C3=CC=C(F)C=C3)=C1C4=CC=CC=C4)NC5=CC=C(O)C=C5

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease; Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Drug Metabolite

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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