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4-Aminonaphthalimide

$32$290

Products Details

Product Description

– 4-Aminonaphthalimide is a potent PARP inhibitor and potentiates the cytotoxicity of γ-radiation in cancer cells[1].

Web ID

– HY-15276

Storage Temperature

– -20°C (Powder, protect from light)

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C12H8N2O2

References

– [1]Schlicker A, et al. 4-Amino-1,8-naphthalimide: a novel inhibitor of poly(ADP-ribose) polymerase and radiation sensitizer. Int J Radiat Biol. 1999 Jan;75(1):91-100.

CAS Number

– 1742-95-6

Molecular Weight

– 212.20

Compound Purity

– 97.0

SMILES

– O=C1NC(C2=CC=C(N)C3=CC=CC1=C23)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– PARP

Pathway

– Cell Cycle/DNA Damage;Epigenetics

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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