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Products Details
Product Description
– 4′-Hydroxywogonin (8-Methoxyapigenin), a flavonoid, could be isolated from a variety of plants including Scutellaria barbata and Verbena littoralis. 4′-Hydroxywogonin has anti-inflammatory activity via TAK1/IKK/NF-κB, MAPKs and PI3/AKT signaling pathways. 4′-Hydroxywogonin inhibits angiogenesis by disrupting PI3K/AKT signaling. 4′-Hydroxywogonin inhibits cell proliferation and induces apoptosis[1][2][3].
Web ID
– HY-N1904
Shipping
– Room temperature
Molecular Formula
– C16H12O6
References
– [1]Fan C, et, al. 4′-Hydroxywogonin suppresses lipopolysaccharide-induced inflammatory responses in RAW 264.7 macrophages and acute lung injury mice. PLoS One. 2017 Aug 8;12(8):e0181191.
CAS Number
– 57096-02-3
Molecular Weight
– 300.26
SMILES
– O=C1C=C(C2=CC=C(O)C=C2)OC3=C(OC)C(O)=CC(O)=C13
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Akt;Apoptosis;Bcl-2 Family;Caspase;IKK;Interleukin Related;NF-κB;p38 MAPK;PI3K;Reactive Oxygen Species;TNF Receptor
Pathway
– Apoptosis;Immunology/Inflammation;MAPK/ERK Pathway;Metabolic Enzyme/Protease;NF-κB;PI3K/Akt/mTOR
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
