Download Files:
3β-Acetoxy-hop-22(29)-ene
SKU
HY-N10439-Get quote
Category Natural Products
Tags Glucosidase, Inflammation/Immunology, Metabolic Enzyme/Protease
Products Details
Product Description
– 3β-Acetoxy-hop-22(29)-ene (compound 1) is a potent anti-inflammatory agent. 3β-Acetoxy-hop-22(29)-ene shows high inhibitory activity of yeast α-glucosidase, with an IC50 of 5.74 μM. 3β-Acetoxy-hop-22(29)-ene inhibits MPO (myeloperoxidase) activity in a dose-dependent manner in mouse ear edema model induced by 12-O-tetradecanoylphorbol acetate (TPA), with an IC50 of 0.23 μmol/ear[1].
Web ID
– HY-N10439
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C32H52O2
References
– [1]López-Huerta FA, et al. Hopane-type triterpenes from Cnidoscolus spinosus and their bioactivities. Bioorg Chem. 2020 Jul;100:103919.
CAS Number
– 76582-61-1
Molecular Weight
– 468.75
SMILES
– C[C@]12[C@@](CC[C@@]3([H])[C@]2(CC[C@]4([H])[C@@]3(CC[C@@H]4C(C)=C)C)C)([H])[C@@]5([C@@](C(C)([C@H](CC5)OC(C)=O)C)([H])CC1)C
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Glucosidase
Pathway
– Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.