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Products Details
Product Description
– (3S,5R)-Fluvastatin sodium ((3S,5R)-XU 62-320) is the (3S,5R)-enantiomer of Fluvastatin. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1].
Web ID
– HY-14664C
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H25FNNaO4
References
– [1]Araújo FA, Rocha MA, Capettini LS, et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (fluvastatin) decreases inflammatory angiogenesis in mice. APMIS. 2012 24.
CAS Number
– 94061-81-1
Molecular Weight
– 433.45
SMILES
– FC1=CC=C(C2=C(/C=C/[C@H](O)C[C@H](O)CC(O[Na])=O)N(C(C)C)C3=C2C=CC=C3)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– HMG-CoA Reductase (HMGCR)
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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