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Products Details
Product Description
– 3CPLro-IN-2 (compound C1) is a potent and orally active inhibitor of SARS-CoV-2 3CLpro with an IC50 and Ki of 1.55 and 6.09 μM, respectively. 3-Chymotrypsin-like cysteine protease (3CLpro) is an indispensable protein in viral replication and represents an attractive agent target for fighting COVID-19[1].
Web ID
– HY-144263
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C32H24BrNO2
References
– [1]Zhang JW, et al. Discovery of 9,10-dihydrophenanthrene derivatives as SARS-CoV-2 3CLpro inhibitors for treating COVID-19. Eur J Med Chem. 2022;228:114030.
CAS Number
– 2758278-51-0
Molecular Weight
– 534.44
SMILES
– OCC1CC2=C(C3=C(C=CC(C4=CC=C(C=C4)Br)=C31)O)C=CC=C2C5=NC=CC(C6=CC=CC=C6)=C5
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– SARS-CoV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
