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3CPLro-IN-1
Products Details
Product Description
– 3CPLro-IN-1 (compound A17) is a potent and orally active inhibitor of SARS-CoV-2 3CLpro with an IC50 of 5.65 μM. 3-Chymotrypsin-like cysteine protease (3CLpro) is an indispensable protein in viral replication and represents an attractive agent target for fighting COVID-19[1].
Web ID
– HY-144260
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C29H25NO3
References
– [1]Zhang JW, et al. Discovery of 9,10-dihydrophenanthrene derivatives as SARS-CoV-2 3CLpro inhibitors for treating COVID-19. Eur J Med Chem. 2022;228:114030.
CAS Number
– 2432956-06-2
Molecular Weight
– 435.51
SMILES
– O=C(C)OCC1C2=C(C)C=CC(O)=C2C3=CC=CC(C4=NC=CC(C5=CC=CC=C5)=C4)=C3C1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– SARS-CoV
Pathway
– Anti-infection
Product type
– Reference compound
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