Products Details

Product Description

– 3CPLro-IN-1 (compound A17) is a potent and orally active inhibitor of SARS-CoV-2 3CLpro with an IC50 of 5.65 μM. 3-Chymotrypsin-like cysteine protease (3CLpro) is an indispensable protein in viral replication and represents an attractive agent target for fighting COVID-19[1].

Web ID

– HY-144260

Shipping

– Room temperature

Applications

– COVID-19-anti-virus

Molecular Formula

– C29H25NO3

References

– [1]Zhang JW, et al. Discovery of 9,10-dihydrophenanthrene derivatives as SARS-CoV-2 3CLpro inhibitors for treating COVID-19. Eur J Med Chem. 2022;228:114030.

CAS Number

– 2432956-06-2

Molecular Weight

– 435.51

SMILES

– O=C(C)OCC1C2=C(C)C=CC(O)=C2C3=CC=CC(C4=NC=CC(C5=CC=CC=C5)=C4)=C3C1

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– SARS-CoV

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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