Products Details

Product Description

– 3,7-DMF is an orally active inhibitor of TGF-β1-induced activation of HSCs. 3,7-DMF induces antioxidant genes and quenches ROS away, which can be used to study liver fibrosis[1].

Web ID

– HY-155786

Shipping

– Room temperature

Molecular Formula

– C17H14O4

References

– [1]Hyomin Park , et al. Discovery of 3,7-dimethoxyflavone that inhibits liver fibrosis based on dual mechanisms of antioxidant and inhibitor of activated hepatic stellate cell. Free Radic Biol Med.2023, 204.

CAS Number

– 20950-52-1

Molecular Weight

– 282.29

SMILES

– O=C1C(OC)=C(C2=CC=CC=C2)OC3=C1C=CC(OC)=C3

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– 10 mM in DMSO

Target

– TGF-beta/Smad

Pathway

– Stem Cell/Wnt;TGF-beta/Smad

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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