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3,3′-Diiodo-L-thyronine-13C6
SKU
HY-129974S-Get quote
Category Isotope-Labeled Compounds
Tags COX;Endogenous Metabolite, Immunology/Inflammation;Metabolic Enzyme/Protease, Metabolic Disease
Products Details
Product Description
– 3,3′-Diiodo-L-thyronine-13C6 is the 13C labeled 3,3′-Diiodo-L-thyronine[1]. 3,3′-Diiodo-L-thyronine (3,3′-T2) is an endogenous metabolite of thyroid hormone. 3,3′-Diiodo-L-thyronine significantly enhances COX activity[2][3].
Web ID
– HY-129974S
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C9 13C6H13I2NO4
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Lorenzini L, et al. Assay of Endogenous 3,5-diiodo-L-thyronine (3,5-T2) and 3,3′-diiodo-L-thyronine (3,3′-T2) in Human Serum: A Feasibility Study. Front Endocrinol (Lausanne). 2019 Feb 19;10:88.|[3]Lanni A, et al. Rapid stimulation in vitro of rat liver cytochrome oxidase activity by 3,5-diiodo-L-thyronine and by 3,3′-diiodo-L-thyronine. Mol Cell Endocrinol. 1994 Feb99(1):89-94.|[4]Chen X, et al. Simultaneous quantification of T4, T3, rT3, 3,5-T2 and 3,3′-T2 in larval zebrafish (Danio rerio) as a model to study exposure to polychlorinated biphenyls. Biomed Chromatogr. 2018 Jun32(6):e4185.
CAS Number
– 1217459-13-6
Molecular Weight
– 531.03
SMILES
– IC(C=C(C=C1)C[C@H](N)C(O)=O)=C1O[13C]2=[13CH][13C](I)=[13C]([13CH]=[13CH]2)O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– COX;Endogenous Metabolite
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease
Product type
– Isotope-Labeled Compounds
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