Products Details

Product Description

– 3,3′-Diiodo-L-thyronine-13C6 is the 13C labeled 3,3′-Diiodo-L-thyronine[1]. 3,3′-Diiodo-L-thyronine (3,3′-T2) is an endogenous metabolite of thyroid hormone. 3,3′-Diiodo-L-thyronine significantly enhances COX activity[2][3].

Web ID

– HY-129974S

Shipping

– Room temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C9 13C6H13I2NO4

References

– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Lorenzini L, et al. Assay of Endogenous 3,5-diiodo-L-thyronine (3,5-T2) and 3,3′-diiodo-L-thyronine (3,3′-T2) in Human Serum: A Feasibility Study. Front Endocrinol (Lausanne). 2019 Feb 19;10:88.|[3]Lanni A, et al. Rapid stimulation in vitro of rat liver cytochrome oxidase activity by 3,5-diiodo-L-thyronine and by 3,3′-diiodo-L-thyronine. Mol Cell Endocrinol. 1994 Feb99(1):89-94.|[4]Chen X, et al. Simultaneous quantification of T4, T3, rT3, 3,5-T2 and 3,3′-T2 in larval zebrafish (Danio rerio) as a model to study exposure to polychlorinated biphenyls. Biomed Chromatogr. 2018 Jun32(6):e4185.

CAS Number

– 1217459-13-6

Molecular Weight

– 531.03

SMILES

– IC(C=C(C=C1)C[C@H](N)C(O)=O)=C1O[13C]2=[13CH][13C](I)=[13C]([13CH]=[13CH]2)O

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– 10 mM in DMSO

Target

– COX;Endogenous Metabolite

Pathway

– Immunology/Inflammation;Metabolic Enzyme/Protease

Product type

– Isotope-Labeled Compounds

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

My Cart
Close Wishlist
Close Recently Viewed
Categories

Please fill out this form to request the file. We will send it to your Email address shortly. Thanks.

Please enable JavaScript in your browser to complete this form.

=

Please fill out this form to request the pricing.
We will send it to your email address shortly.
Thanks.

Please enable JavaScript in your browser to complete this form.

=