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Products Details
Product Description
– 3,3′-Diethyl-9-methylthiacarbocyanine iodide is a cyanine dye, also a tau aggregation inhibitor, with an IC50 value of 0.28 μM for tau. 3,3′-Diethyl-9-methylthiacarbocyanine iodide can cause misfunction of the microtubule cytoskeleton. 3,3′-Diethyl-9-methylthiacarbocyanine iodide can be used for researching Alzheimer’s disease[1].
Web ID
– HY-111935
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C22H23IN2S2
References
– [1]Chang E, et al. Structure-activity relationship of cyanine tau aggregation inhibitors. J Med Chem. 2009 Jun 11;52(11):3539-47.
CAS Number
– 3065-79-0
Molecular Weight
– 506.47
SMILES
– CC(/C=C1SC2=CC=CC=C2N/1CC)=CC3=[N+](CC)C4=CC=CC=C4S3.[I-]
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
