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3-O-Methyldopa

$120$350

Products Details

Product Description

– 3-O-Methyldopa (3-Methoxy-L-tyrosine) is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of l-DOPA and dopamine[1].

Web ID

– HY-113468A

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C10H13NO4

References

– [1]Masato Asanuma, et al. 3-O-Methyldopa inhibits astrocyte-mediated dopaminergic neuroprotective effects of L-DOPA. BMC Neurosci. 2016 Jul 25;17(1):52.

CAS Number

– 300-48-1

Molecular Weight

– 211.21

Compound Purity

– 98.0

SMILES

– N[C@@H](CC1=CC=C(O)C(OC)=C1)C(O)=O

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– H2O : 16.67 mg/mL (ultrasonic)

Target

– Dopamine Receptor;Endogenous Metabolite

Pathway

– GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling

Product type

– Natural Products

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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