3′-Deoxyuridine-5′-triphosphate (trisodium)

$1,600

Only 1000 item(s) left in stock.

Products Details

Product Description

– 3′-Deoxyuridine-5′-triphosphate trisodium (3′-dUTP trisodium) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3′-Deoxyuridine-5′-triphosphate trisodium strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM[1].

Web ID

– HY-135780A

Storage Temperature

– -20°C (Powder, sealed storage, away from moisture and light)

Shipping

– Blue Ice

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C9H12N2Na3O14P3

References

– [1]M Saneyoshi, et al. Inhibitory Effects of 3’deoxycytidine 5′-triphosphate and 3′-deoxyuridine 5′-triphosphate on DNA-dependent RNA Polymerases I and II Purified From Dictyostelium Discoideum Cells. Nucleic Acids Res. 1981 Jul 10;9(13):3129-38.

Molecular Weight

– 534.09

Compound Purity

– 99.69

SMILES

– O=P(O)(O[Na])OP(OP(OC[C@@H](O1)C[C@@H](O)[C@@H]1N2C(NC(C=C2)=O)=O)(O[Na])=O)(O[Na])=O

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– H2O : 20 mg/mL (ultrasonic)

Target

– DNA/RNA Synthesis;Endogenous Metabolite;Nucleoside Antimetabolite/Analog

Pathway

– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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