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3′-Deoxyuridine-5′-triphosphate (trisodium)
SKU
HY-135780A-1 mg
Category Reference compound
Tags Cell Cycle/DNA Damage;Metabolic Enzyme/Protease, DNA/RNA Synthesis;Endogenous Metabolite;Nucleoside Antimetabolite/Analog, Metabolic Disease
$1,600
Only 1000 item(s) left in stock.
Products Details
Product Description
– 3′-Deoxyuridine-5′-triphosphate trisodium (3′-dUTP trisodium) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3′-Deoxyuridine-5′-triphosphate trisodium strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM[1].
Web ID
– HY-135780A
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture and light)
Shipping
– Blue Ice
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C9H12N2Na3O14P3
References
– [1]M Saneyoshi, et al. Inhibitory Effects of 3’deoxycytidine 5′-triphosphate and 3′-deoxyuridine 5′-triphosphate on DNA-dependent RNA Polymerases I and II Purified From Dictyostelium Discoideum Cells. Nucleic Acids Res. 1981 Jul 10;9(13):3129-38.
Molecular Weight
– 534.09
Compound Purity
– 99.69
SMILES
– O=P(O)(O[Na])OP(OP(OC[C@@H](O1)C[C@@H](O)[C@@H]1N2C(NC(C=C2)=O)=O)(O[Na])=O)(O[Na])=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– H2O : 20 mg/mL (ultrasonic)
Target
– DNA/RNA Synthesis;Endogenous Metabolite;Nucleoside Antimetabolite/Analog
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.