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Products Details
Product Description
– 3′-Deoxyuridine-5′-triphosphate (3′-dUTP) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3′-Deoxyuridine-5′-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM[1].
Web ID
– HY-135780
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C9H15N2O14P3
References
– [1]M Saneyoshi, et al. Inhibitory Effects of 3’deoxycytidine 5′-triphosphate and 3′-deoxyuridine 5′-triphosphate on DNA-dependent RNA Polymerases I and II Purified From Dictyostelium Discoideum Cells. Nucleic Acids Res. 1981 Jul 10;9(13):3129-38.
CAS Number
– 69199-40-2
Molecular Weight
– 468.14
SMILES
– O=P(O)(O)OP(OP(OC[C@@H](O1)C[C@@H](O)[C@@H]1N2C(NC(C=C2)=O)=O)(O)=O)(O)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis;Endogenous Metabolite;Nucleoside Antimetabolite/Analog
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
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