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3-(4-Pyridyl)indole
$145 – $230
Products Details
Product Description
– 3-(4-Pyridyl)indole (Rockout) is a Rho-kinase (ROCK) inhibitor, with an IC50 of 25 μM. 3-(4-Pyridyl)indole can inhibit blebbing and cause dissolution of actin stress fibers in a wound healing assay[1].
Web ID
– HY-112362
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C13H10N2
References
– [1]Yarrow JC, et, al. Screening for cell migration inhibitors via automated microscopy reveals a Rho-kinase inhibitor. Chem Biol. 2005 Mar;12(3):385-95.
CAS Number
– 7272-84-6
Molecular Weight
– 194.23
SMILES
– C1(C2=CC=NC=C2)=CNC3=C1C=CC=C3
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– ROCK
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton;Stem Cell/Wnt;TGF-beta/Smad
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
