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Products Details
Product Description
– 3-(3-Phenoxybenzyl)amino-β-carboline is a potent tubulin inhibitor. 3-(3-Phenoxybenzyl)amino-β-carboline promotes selective degradation of αβ-tubulin heterodimers. 3-(3-Phenoxybenzyl)amino-β-carboline induces G2/M phase cell cycle arrest and apoptosis. 3-(3-Phenoxybenzyl)amino-β-carboline exhibits anticancer activity[1].
Web ID
– HY-150511
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H19N3O
References
– [1]Yang J, et al. Small Molecules Promote Selective Denaturation and Degradation of Tubulin Heterodimers through a Low-Barrier Hydrogen Bond. J Med Chem. 2022 Jun 28.
CAS Number
– 1327080-54-5
Molecular Weight
– 365.43
SMILES
– C(N1)(C=NC(NCC2=CC=CC(OC3=CC=CC=C3)=C2)=C4)=C4C5=C1C=CC=C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Microtubule/Tubulin
Pathway
– Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
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