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264W94
SKU
HY-19264-Get quote
Category Reference compound
Tags Apical Sodium-Dependent Bile Acid Transporter, Membrane Transporter/Ion Channel, Metabolic Disease
Products Details
Product Description
– 264W94 is a potent ileal bile acid transporter (IBAT) inhibitor and a new cholesterol lowering agent. 264W94 has CYP7A1 induction, and antilipemic action[1].
Web ID
– HY-19264
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C23H31NO4S
References
– [1]Root C, et al. Ileal bile acid transporter inhibition, CYP7A1 induction, and antilipemic action of 264W94. J Lipid Res. 2002 Aug;43(8):1320-30.|[2]Chen L, et al. Inhibition of apical sodium-dependent bile acid transporter as a novel treatment for diabetes. Am J Physiol Endocrinol Metab. 2012 Jan 1;302(1):E68-76.
CAS Number
– 178961-24-5
Molecular Weight
– 417.56
SMILES
– COC1=C(OC)C=C(C2=C1)[C@@H](C3=CC=CC=C3)N[C@](CC)(CCCC)CS2(=O)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Apical Sodium-Dependent Bile Acid Transporter
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
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