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Products Details
Product Description
– (24E)-3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid is a potent PTP1B inhibitor, with an IC50 of 0.4 μM. (24E)-3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid exhibits potent PTP1B inhibitory activity without cytotoxicity[1].
Web ID
– HY-N1783
Shipping
– Room temperature
Molecular Formula
– C31H48O6
References
– [1]Maarisit W, et al. Protein tyrosine phosphatase 1B inhibitory properties of seco-cucurbitane triterpenes obtained from fruiting bodies of Russula lepida. J Nat Med. 2017 Jan;71(1):334-337.
CAS Number
– 329975-47-5
Molecular Weight
– 516.71
SMILES
– O=C(O)CC[C@@H]([C@@]1(C)[C@]2([H])[C@]3(C)CC[C@@]([C@H](C)CC/C=C(C(O)=O)C)(C)[C@@]3(C)CC1)/C(CC2)=C(C(O)=O)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Phosphatase
Pathway
– Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
