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2′,3′,5′-Tri-O-benzoyl-5-azacytidine

Products Details

Product Description

– 2′,3′,5′-Tri-O-benzoyl-5-azacytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

Web ID

– HY-154397

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C29H24N4O8

References

– [1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.

CAS Number

– 28998-36-9

Molecular Weight

– 556.52

SMILES

– NC(N=CN1[C@@H]2O[C@@H]([C@H]([C@H]2OC(C3=CC=CC=C3)=O)OC(C4=CC=CC=C4)=O)COC(C5=CC=CC=C5)=O)=NC1=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Nucleoside Antimetabolite/Analog

Pathway

– Cell Cycle/DNA Damage

Product type

– Oligonucleotides

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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