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20-Deoxyingenol
$120 – $216
Products Details
Product Description
– 20-Deoxyingenol, a diterpene, is isolated from the roots of Euphorbia kansui. 20-Deoxyingenol can promote autophagy and lysosomal biogenesis by promoting the nuclear translocation of transcription factor EB (TFEB) in vitro. 20-Deoxyingenol can be used for the research of osteoarthritis (OA)[1][2].
Web ID
– HY-N0866
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C20H28O4
References
– [1]Uemura D, et, al. Isolation and structures of 20-deoxyingenol new diterpene, derivatives and ingenol derivative obtained from “kansui”. Tetrahedron Letters. 1974; 15(29): 2527-2528.|[2]Gu M, et, al. 20-Deoxyingenol alleviates osteoarthritis by activating TFEB in chondrocytes. Pharmacol Res. 2021 Jan 15;165:105361.
CAS Number
– 54706-99-9
Molecular Weight
– 332.43
Compound Purity
– 99.84
SMILES
– O=C1[C@@]2(C=C(C)[C@@H]3O)[C@]3(O)[C@H](O)C(C)=C[C@@]1([H])[C@@]4([H])[C@@](C4(C)C)([H])C[C@H]2C
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– Autophagy
Pathway
– Autophagy
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
