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Products Details
Product Description
– 2-PAT, an analogue of Rasagiline and Selegiline, a reversible MAO-A inhibitor with an IC50 of 0.721 μM. 2-PAT is an inactivator of MAO-B with an IC50 of 14.6 μM. 2-PAT has?the?potential?for?Parkinson’s disease and depression?research[1]. 2-PAT is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-143438
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C13H15N
References
– [1]Letitia Meiring, et al. The evaluation of N-propargylamine-2-aminotetralin as an inhibitor of monoamine oxidase. Bioorg Med Chem Lett. 2022 Jul 1;67:128746.
CAS Number
– 134467-58-6
Molecular Weight
– 185.26
SMILES
– C#CCNC1CC2=C(C=CC=C2)CC1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Monoamine Oxidase
Isoform
– MAO-A;MAO-B
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
